Quality Assurance in the Pathology Laboratory

Forensic, Technical, and Ethical Aspects

 Edited by Maciej J. Bogusz

Contents

Part I
Quality Assurance of Chemometric Methods and Pathology: Selected Topics

1 The Preanalytical Phase in Quality Assurance 

Giuseppe Lippi and Gian Cesare Guidi

2 Quality Assurance of Point-of-Care and On-Site Drug Testing 

James H. Nichols

3 Quality Assurance of Identification with Chromatographic–Mass Spectrometric Methods 

Maciej J. Bogusz

4 Quality Assurance of Quantification Using Chromatographic Methods with Linear Relation between Dose and Detector Response 

Georg Schmitt and Rolf Aderjan

Part II
Quality Assurance Aspects of Newly Emerging Methods in Pathology and Laboratory Medicine

5 Pharmacogenomics, Personalized Medicine, and Personalized Justice Influencing the Quality and Practice of Forensic Science 

Steven H.Y. Wong

6 Quality Aspects in Autopsy versus Virtopsy  

Michael J. Thali and Stephan A. Bolliger

Part III
Accreditation, Standards, and Education: Their Role in Maintaining Quality

7 Role of Accreditation Procedures in Maintaining Quality 

Maciej J. Bogusz and Huda Hassan

8 Role of Governmental and Professional Organizations in Setting Quality Standards in Pathology and Laboratory Medicine and Related Areas 

Maciej J. Bogusz

9 Education and Training in the Changing Environment of Pathology and Laboratory Medicine 

Gian Cesare Guidi and Giuseppe Lippi

10 Quality Assurance Aspects of Interpretation of Results in Clinical and Forensic Toxicology 

Katrin M. Kirschbaum and Frank Musshoff

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Bioanalytical chemistry - Mikkelsen & Corton

CLINICAL CHEMISTRY (Organ Function Tests, Laboratory Investigations and Inborn Metabolic Diseases)

CLINICAL CHEMISTRY 

(Organ Function Tests, Laboratory Investigations and Inborn Metabolic Diseases)

Clinical Laboratory Science : The Basics and Routine Techniques

Clinical Laboratory Science

The Basics and Routine Techniques

POLYURIA AND POLYDIPSIA

CASE 1:

 POLYURIA AND POLYDIPSIA 

PHYSICAL CHEMISTRY

Sixth Edition

Contents

CHAPTER 1 Thermodynamics
CHAPTER 2 The First Law of Thermodynamics
CHAPTER 3 The Second Law of Thermodynamics
CHAPTER 4 Material Equilibrium
CHAPTER 5  Standard
CHAPTER 6 Thermodynamic Functions of Reaction
CHAPTER 7 Reaction Equilibrium in Ideal Gas Mixtures
CHAPTER 8 One-Component Phase Equilibrium and Surfaces
CHAPTER 9 Real Gases
CHAPTER 10 Solutions
CHAPTER 11 Nonideal Solutions
CHAPTER 12 Reaction Equilibrium in Nonideal Systems
CHAPTER 13 Multicomponent Phase Equilibrium
CHAPTER 14 Electrochemical Systems
CHAPTER 15 Kinetic Theory of Gases
CHAPTER 16 Transport Processes
CHAPTER 17 Reaction Kinetics
CHAPTER 18 Quantum Mechanics
CHAPTER 19 Atomic Structure
CHAPTER 20 Molecular Electronic Structure
CHAPTER 21 Spectroscopy and Photochemistry
CHAPTER 22 Statistical Mechanics
CHAPTER 23 Theories of Reaction Rates
CHAPTER 24 Solids and Liquids

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CLINICAL CHEMISTRY (Organ Function Tests, Laboratory Investigations and Inborn Metabolic Diseases)

CLINICAL CHEMISTRY 

(Organ Function Tests, Laboratory Investigations and Inborn Metabolic Diseases)

Contents

Part 1: Organ Function Tests 1-82

1. Renal Function Tests .................................................................................................................... 3

2. Liver Function Tests ....................................................................................................................... 15

3. Gastric Function Tests .................................................................................................................... 36

4. Thyroid Function Tests .................................................................................................................. 47

5. Adrenocortical Function Tests ...................................................................................................... 60

6. Pancreatic Function Tests .............................................................................................................. 72

Part 2: Laboratory Investigations 83-262

7. Hyperglycaemia .............................................................................................................................. 85

8. Hypoglycaemia ................................................................................................................................ 96

9. Hypercalcaemia ............................................................................................................................. 106

10. Hypocalcaemia .............................................................................................................................. 118

11. Hypercortisolism ........................................................................................................................... 125

12. Hypocortisolism ............................................................................................................................ 132

13. Hyperlipoproteinaemias (Hyperlipidaemias) ......................................................................... 139

14. Jaundice .......................................................................................................................................... 149

15. Neonatal Jaundice ......................................................................................................................... 159

16. Hyperthyroidism ........................................................................................................................... 171

17. Hypothyroidism ............................................................................................................................ 182

18. Malabsorption Syndrome ............................................................................................................ 191

19. Obesity ............................................................................................................................................ 204

20. Polyuria ........................................................................................................................................... 212

21. Haemolytic Transfusion Reaction ............................................................................................. 218

22. Haemolytic Anaemia .................................................................................................................... 227

23. Iron Deficiency Anaemia ............................................................................................................ 240

24. Macrocytic Megaloblastic Anaemia .......................................................................................... 248

Part 3: Miscellaneous 263-290

25. Enzymes and Isoenzymes in Clinical Medicine ..................................................................... 265

26. Oncogenic Markers (Tumour Markers) .................................................................................... 281

Part 4: Inborn Metabolic Diseases (Inborn Errors of Metabolism) 291-376

27. Inborn Metabolic Diseases (Inborn Errors of Metabolism) ................................................. 293

A. Disorders of Carbohydrate Metabolism .............................................................................. 295

B. Amino Acid Metabolic Disorders ......................................................................................... 327

C. Disorders of Lipid Metabolism ............................................................................................. 358

D. Inborn Errors of Defective DNA Repair and Purines/Pyrimidine Metabolism ........... 365

References ............................................................................................................. 377

Index ...................................................................................................................... 379

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