Bioanalytical chemistry - Mikkelsen & Corton

CLINICAL CHEMISTRY (Organ Function Tests, Laboratory Investigations and Inborn Metabolic Diseases)

CLINICAL CHEMISTRY 

(Organ Function Tests, Laboratory Investigations and Inborn Metabolic Diseases)

Clinical Laboratory Science : The Basics and Routine Techniques

Clinical Laboratory Science

The Basics and Routine Techniques

POLYURIA AND POLYDIPSIA

CASE 1:

 POLYURIA AND POLYDIPSIA 

PHYSICAL CHEMISTRY

Sixth Edition

Contents

CHAPTER 1 Thermodynamics
CHAPTER 2 The First Law of Thermodynamics
CHAPTER 3 The Second Law of Thermodynamics
CHAPTER 4 Material Equilibrium
CHAPTER 5  Standard
CHAPTER 6 Thermodynamic Functions of Reaction
CHAPTER 7 Reaction Equilibrium in Ideal Gas Mixtures
CHAPTER 8 One-Component Phase Equilibrium and Surfaces
CHAPTER 9 Real Gases
CHAPTER 10 Solutions
CHAPTER 11 Nonideal Solutions
CHAPTER 12 Reaction Equilibrium in Nonideal Systems
CHAPTER 13 Multicomponent Phase Equilibrium
CHAPTER 14 Electrochemical Systems
CHAPTER 15 Kinetic Theory of Gases
CHAPTER 16 Transport Processes
CHAPTER 17 Reaction Kinetics
CHAPTER 18 Quantum Mechanics
CHAPTER 19 Atomic Structure
CHAPTER 20 Molecular Electronic Structure
CHAPTER 21 Spectroscopy and Photochemistry
CHAPTER 22 Statistical Mechanics
CHAPTER 23 Theories of Reaction Rates
CHAPTER 24 Solids and Liquids

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CLINICAL CHEMISTRY (Organ Function Tests, Laboratory Investigations and Inborn Metabolic Diseases)

CLINICAL CHEMISTRY 

(Organ Function Tests, Laboratory Investigations and Inborn Metabolic Diseases)

Contents

Part 1: Organ Function Tests 1-82

1. Renal Function Tests .................................................................................................................... 3

2. Liver Function Tests ....................................................................................................................... 15

3. Gastric Function Tests .................................................................................................................... 36

4. Thyroid Function Tests .................................................................................................................. 47

5. Adrenocortical Function Tests ...................................................................................................... 60

6. Pancreatic Function Tests .............................................................................................................. 72

Part 2: Laboratory Investigations 83-262

7. Hyperglycaemia .............................................................................................................................. 85

8. Hypoglycaemia ................................................................................................................................ 96

9. Hypercalcaemia ............................................................................................................................. 106

10. Hypocalcaemia .............................................................................................................................. 118

11. Hypercortisolism ........................................................................................................................... 125

12. Hypocortisolism ............................................................................................................................ 132

13. Hyperlipoproteinaemias (Hyperlipidaemias) ......................................................................... 139

14. Jaundice .......................................................................................................................................... 149

15. Neonatal Jaundice ......................................................................................................................... 159

16. Hyperthyroidism ........................................................................................................................... 171

17. Hypothyroidism ............................................................................................................................ 182

18. Malabsorption Syndrome ............................................................................................................ 191

19. Obesity ............................................................................................................................................ 204

20. Polyuria ........................................................................................................................................... 212

21. Haemolytic Transfusion Reaction ............................................................................................. 218

22. Haemolytic Anaemia .................................................................................................................... 227

23. Iron Deficiency Anaemia ............................................................................................................ 240

24. Macrocytic Megaloblastic Anaemia .......................................................................................... 248

Part 3: Miscellaneous 263-290

25. Enzymes and Isoenzymes in Clinical Medicine ..................................................................... 265

26. Oncogenic Markers (Tumour Markers) .................................................................................... 281

Part 4: Inborn Metabolic Diseases (Inborn Errors of Metabolism) 291-376

27. Inborn Metabolic Diseases (Inborn Errors of Metabolism) ................................................. 293

A. Disorders of Carbohydrate Metabolism .............................................................................. 295

B. Amino Acid Metabolic Disorders ......................................................................................... 327

C. Disorders of Lipid Metabolism ............................................................................................. 358

D. Inborn Errors of Defective DNA Repair and Purines/Pyrimidine Metabolism ........... 365

References ............................................................................................................. 377

Index ...................................................................................................................... 379

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 The ABC of CBC Complet Blood Count Book

Contents

1. Introduction and Significance of CBC 1

2. Red Blood Cells 6

2. A. Red blood cells 6

2. B. Hemoglobin 8

2. C. Reticulocyte 12

2. D. Hematocrit -packed cell volume (PCV) 14

2. E. Mean corpuscular volume 16

2. F. Mean corpuscular hemoglobin 18

2. G. Mean corpuscular hemoglobin concentration (MCHC) 18

2. H. Red cell distribution width (RDW) 19

3. RBCs on Peripheral Smear 23

3. A. RBCs on peripheral smear 24

3. B. Hemoparasite 32

4. White Blood Cells 41

4. A. WBC count 41

4. B. Polymorphs 46

4. C. Eosinophils 52

4. D. Basophils 53

4. E. Monocytes 54

4. F. Lymphocytes 55

5. Platelets 59

5. A. Platelet count 59

5. B. Disorders of platelets 64

5. C. Mean platelet volume (MPV) 66

5. D. Platelet distribution width (PDW) 67

5. E. Plateletcrit (PCT) 68

5. F. Immature platelet fraction (IPF) 68

6. Manual v/s Automation in Hematology 70

7. General Principle of Histogram Generation and Interpretation 82

8. Histograms 87

9. Scattergram 127

10. Case Studies 131

11. Quality Control 162

Bibliography 171

Index 173

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